UC San Diego Teams with Other Universities and Audi to Help Urban Drivers
UC San Diego Teams with Other Universities and Audi to Help Urban Drivers
Bioengineers ‘Pump’ Life Into Post-Heart Attack Therapies
San Diego, CA, January 18, 2011 — Bioengineers at UC San Diego are one step closer to improving therapies for heart attack victims. A paper recently published in Biomaterials called “Hydrogels with time-dependent material properties enhance cardiomyocyte differentiation in vitro,” describes how the researchers measured the increase in stiffness that occurs in heart muscle as it develops and then mimicked that change in a modified version of a biological material called hyaluronic acid. Pre-cardiac cells grown on these materials were found to mature into adult heart cells better than when grown on materials that did not stiffen. This process occurred despite not having the proper chemical signals around them and shows how important stiffness can be to cells.